Analytical Development
Capabilities
- Characterization of Proteins and Peptides by charge, mass, molecular weight, HPLC, CD spectrometry, protease finger print, isoelectric point, Capillary Electrophoresis
- Impurity profiling
- Analytical method development and validation of the methods
- Part of the USP team with contribution towards creation of monographs for Biosimilar products
Infrastructure
- Equipment for:
- Identification of Proteins and Peptides
- Peptide mapping
- Impurity profiling
- Glycoproteins and Carbohydrates analysis
- Capillary Zone Electrophoresis
- Amino Acid Analyser
- LCMS with interface ESI and APCI
- HPLC with UV, refractive index and fluorescence detectors
- GC with head space detection
- Characterization of size variants in proteins using MALLS Detector
- ESI-Q-TOF mass spectrometer with UPLC interface for accurate intact mass determination
- Stability chambers
- Concentrators and lyophilizers
- CD Spectropolarimeter